Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
The Effect of Licorice and Probiotics on Nonalcoholic Fatty Liver Disease (NAFLD): A Systematic Review
163
169
EN
Pouya
Rostamizadeh
00000000000000000000
Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
pouyarostamizadeh@gmail.com
Zohreh
Mazloom
0000-0001-5889-7373
Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
zohreh.mazloom@gmail.com
10.30476/ijns.2019.84178.1042
The present studies showed that utilizing complementary and alternative medicine such as herbal remedies, and the use of beneficial gastrointestinal microorganisms, along with lifestyle modifications can contribute to the improvement of non-alcoholic fatty liver disease (NAFLD). The purpose of this study was to summarize the results of the existing studies on the relationship between licorice and probiotic consumption with fatty liver disease. Databases such as Google Scholar, Scopus, and Pubmed databases were searched to find relevant studies. Clinical and experimental trials were selected to be entered into this review article. The articles were evaluated for duplication, title, type of study, study population and variables. Of the 1177 retrieved articles, 17 were selected for full-text review and 5 for structured review. A review of these studies showed that glycyrrhizic acid as an active ingredient of licorice root significantly decreased the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), free fatty acid (FFA), and hepatic steatosis. Also clinical studies showed that consumption of probiotics significantly decreased the levels of (ALT), (AST), total cholesterol (TC) and low density lipoprotein (LDL.C). The findings of this study indicated that the use of glycyrrhizic acid and probiotics contributed to the improvement of NAFLD through synergistic effects.
Non-Alcoholic fatty liver disease,Licorice,Glycyrrhizic acid,Probiotic,Synergy
https://ijns.sums.ac.ir/article_45833.html
https://ijns.sums.ac.ir/article_45833_aea6b76dbd3534fa0874e9778cc218f1.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
The Effects of Vitamin C in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review of Clinical Trials
170
174
EN
Zahra
Mosallanezhad
00000000000000000000
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
mosallanezhad.z@gmail.com
Mohammad
Jalali
https://orcid.org/0000-0001-8133-3875
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
mj.artak@gmail.com
Mohammad Hassan
Eftekhari
0000-0001-5428-1491
Department of Clinical Nutrition,
School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
h_eftekhari@yahoo.com
Afsane
Ahmadi
0000-0001-5163-7368
Research Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran
ahmadia@sums.ac.ir
10.30476/ijns.2019.84611.1049
The present systematic review aimed to investigate the effects of vitamin C on the improvement of chronic obstructive pulmonary disease (COPD). Online databases (PubMed, Scopus, Embase, Cochrane Library and Web of Sciences) were systematically searched to find clinical trials evaluating the effects of vitamin C supplementation on COPD up to July 2019. After excluding irrelevant records, 3 studies were included. Two included studies demonstrated significant effect of vitamin C supplementation on <br /> COPD improvement, but another study did not. In conclusion, vitamin C might have positive effects on COPD patients. But more future studies are needed to reach a definite conclusion.
COPD,Vitamin C,Ascorbic Acid
https://ijns.sums.ac.ir/article_45915.html
https://ijns.sums.ac.ir/article_45915_77c26f2435d7b0463e1e318954da966a.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
Healing Effect of Perovskia Abrotanoides Karel and Expression of VEGF and TGF-Β Genes in Burn Injury of Rats
175
180
EN
Amin
Derakhshanfar
0000-0002-8007-9446
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
derakhshanfar@sums.ac.ir
Davood
Mehrabani
0000-0002-5738-1719
Center of Comparative and Experimental Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
mehrabad@sums.ac.ir
Javad
Moayedi
0000-0001-6154-9468
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
cbrc@sums.ac.ir
Iman
Jamhiri
0000-0002-4772-8678
Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
iman.jamhiri@gmail.com
10.30476/ijns.2019.83490.1035
Background: Burn is a life-threatening problem which can lead to alteration in the expression of several genes. A folk medicine topical ointment made from Perovskia abrotanoides (P. abrotanoides) was extensively used in northern region of Iran for burn wound healing properties. Therefore, the current study aimed to examine the healing potency of P. abrotanoides ointment and the expression patterns of wound healing-related genes in rat experimental model of of burn.<br />Methods: In an experimental study, scald burn was inflicted in 28 adult male Sprague-Dawley rats by pouring 2.5 cc of boiling water into a firm rubber ring (2 cm diameter) on the dorsal surface of skin for 10 seconds. Rats were randomly divided into four groups and treated for 7 consecutive days: P. abrotanoides ointmenttreated group; a vehicle-treated group, which received the complete ointment without P. abrotanoides part; silver sulfadiazine-treated group; and the control group which received no treatment. Animals were sacrificed and a full thickness skin biopsy was taken from the burn site. Finally, the relative quantification of gene expression was performed using the vascular endothelial growth factor (VEGF) and transforming growth factor-β (TGF-β) as target genes and β2-microglobulin (β2M) as a reference gene.<br />Results: VEGF was up-regulated during the first week of healing in P. abrotanoides ointment-treated group; however, the local expression of TGF-β was similar between the groups.<br />Conclusion: P. abrotanoides ointment utilized in Iranian folk medicine can accelerate wound healing by producing VEGF.
Perovskia abrotanoides,Burn,Wound,VEGF,TGF-β
https://ijns.sums.ac.ir/article_45586.html
https://ijns.sums.ac.ir/article_45586_a4b5786e7abf6e858ae42523c0b50172.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
The Effect of Purple Sweet Potato Jelly on Malondialdehyde and Fasting Blood Sugar in Experimental Type 2 Diabetic Rat Model
181
185
EN
Titik Dwi
Noviati
noviatitikdwi@gmail.com
Graduate School of Nutrition Science, Sebelas Maret University, Surakarta, Indonesia
noviatitikdwi@gmail.com
Didik Gunawan
Tamtomo
Graduate School of Nutrition Science, Sebelas Maret University, Surakarta, Indonesia
didiktamtomo@yahoo.com
Sugiarto
Sugiarto
Graduate School of Nutrition Science, Sebelas Maret University, Surakarta, Indonesia
perkenisolo@yahoo.com
10.30476/ijns.2019.83872.1038
Background: Purple sweet potato jelly (Lpomea batatas L. Poir) <br /> can potentially be rich in anthocyanin and fiber with antioxidant and hypoglycemic properties that may be beneficial to T2DM sufferers. This study aimed to find out the influence of purple sweet potato jelly on MDA and FBS in experimental T2DM of rats. <br /> Methods: In an experimental research, 20 male Wistar rats were divided into four groups. Group 1 consisted of T2DM rats fed on standard diet (G1), while group 2, 3 and 4 were fed on standard diet of 7.47 g per 200 g <br /> of body weight containing 1.35 g (G2), 2.7 g (G3) and 5.4 g (G4) of purple sweet potato jelly, respectively. The MDA and FBS levels were checked at day 0 and 14. <br /> Results: After 14th day of intervention, the mean MDA level changed to 0.28±0.84 in G1, -4.08±0.54 in G2, -5.81±0.45 in G3 and -6.56±0.50 nmol/ml in G4, while the MDA level in G1 was significantly different from other groups (P=0.001). The Mean FBS level changed to 3.95±0.68 in G1, -114.06±3.11 in G2, -129.96±4.23 in G3 and -136.78±3.94 mg/dL in G4, whereas the FBS level of G1 was significantly different from other groups (P=0.001). <br /> Conclusion: Our findings revealed that purple sweet potato jelly when consumed for 14 days could significantly decrease MDA and FBS levels in type 2 diabetes mellitus rat model. Therefore, purple sweet potato can be introduced in literature an alternative herbal medicine in treatment of type 2 diabetes mellitus.
Lpomea batatas L. Poir,Purple sweet potato,Type 2 diabetes mellitus Malondialdehyde,Fasting blood sugar
https://ijns.sums.ac.ir/article_45867.html
https://ijns.sums.ac.ir/article_45867_0ce2da8a1c100ac486c192144f366f0b.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
Correlation of Smoking Habits, Physical Activities and Fat Intake with Cognitive Ability in Indonesian Elderly
186
191
EN
Yuniars
Renowening
0000-0001-7629-2837
Postgraduate Student of Nutrition Science, Sebelas Maret University, Ir Sutami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
yuniarsrenowening@gmail.com
Suradi
Suradi
Departement of Public Health, Faculty of Medicine, Sebelas Maret University, Ir Sutami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
radi.samto@gmail.com
Ari
Probandari
Departement of Public Health, Faculty of Medicine, Sebelas Maret University, Ir Sutami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
ari.probandari@staff.uns.ac.id
10.30476/ijns.2019.83497.1037
Background: The aging process that occurs in elderly makes the elderly more vulnerable to health threats, such as decreased cognitive abilities. Lifestyle is a factor that plays an important role in several diseases, such as smoking, lack of physical activity, and consuming unhealthy foods. The purpose of this study was to find the correlation of smoking habit, physical activities and fat intake with cognitive abilities in elderly.<br />Methods: This study used a cross sectional design involving 182 elderly over the age of 60 years in six integrated services post (Posyandu) in Klaten Regency, Indonesia. Data of smoking habits and physical activities were obtained by interview and fat intake was determinated by food recall. Data of cognitive ability was obtained through interview using Mini Mental State Exam (MMSE) questionnaire. Data were tested using Spearman correlation to determine the relationship between variables.<br />Results: The results showed that there was a significant relationship between smoking habit with cognitive ability in elderly (p <0.001). There was a significant relationship between physical activity and cognitive ability in elderly (P=0.001). There was no significant relationship between fat intake and cognitive ability in elderly (P=0.494).<br />Conclusion: Low smoking habits and high physical activity was correlated to a better cognitive function in Indonesian elderly.
smoking habit,Physical Activity,fat intake,cognitive ability
https://ijns.sums.ac.ir/article_45790.html
https://ijns.sums.ac.ir/article_45790_4ac2872da149f8fa70b9d4323d06162f.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
Correlation between Appetite Disorders, Nutritional Status and Smoking Habits in Elderly
192
196
EN
Ahmad
David Royyifi Arifin
0000-0002-2495-8980
Postgraduate Student of Nutrition Science, Sebelas Maret University, Ir Sutami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
royyifi@gmail.com
Suradi
Suradi
Departement of Public Health, Faculty of Medicine, Sebelas Maret University, Ir Surami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
radi.samto@gmail.com
Diffah
Hanim
Departement of Public Health, Faculty of Medicine, Sebelas Maret University, Ir Surami Street No 36A Kentingan, Jebres, Surakarta 57126, Indonesia
diffah@staf.uns.ac.id
10.30476/ijns.2019.83495.1036
Introduction: Health is an aspect that needs attention in the elderly. So many factors can affect to health of the elderly, one of them is lifestyle. Poor lifestyles such as smoking can increase a person's risk of disease. Smoking has a large impact on the elderly like reducing appetite and further inmpact is weight loss. This can result in the occurrence of underweight in the elderly. The aims of the study to analyze the correlation between decreased appetite, nutritional status with smoking habits in elderly. Methods and Materials: This was a cross-sectional study involving 182 elderly. Decreased appetite was obtained interview using the Simplified Nutritional Appetite Questionnaire (SNAQ) questionnaire. Nutritional status was obtained based on anthropometric measurements of body weight and height calculated using the formula Body Mass Index (BMI), and smoking habits obtained from interviews using a research questionnaire. The data uses obtained were analyzed using the Spearman test with a p-value
Appetite,Nutrition,Smoking,Elderly
https://ijns.sums.ac.ir/article_45828.html
https://ijns.sums.ac.ir/article_45828_9d04f9dd991eaac106fdedf269e68886.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
The Correlation between Body Mass Index, Protein Intake, and Quality of Life in Elderly
197
201
EN
Dian
Nafies
0000-0001-5310-4303
Postgraduate Program of Nutrition Science, Sebelas Maret University, Ir. Sutami Street No. 36A, Kentingan, Jebres, Surakarta 57126, Indonesia
diannafies19@gmail.com
Diffah
Hanim
Nutrition of Science Study Program, Postgraduate Program, Sebelas Maret University, Kentingan, Jebres, Surakarta, Indonesia
diffah@staff.uns.ac.id
Suminah
Suminah
Agricultural Extension and Communication Study Program, Faculty of Agriculture, Sebelas Maret University, Ir. Sutami Street No. 36A, Kentingan, Jebres, Surakarta 57126, Indonesia
suminah@staff.uns.ac.id
10.30476/ijns.2019.83424.1034
Background: The elderly is an age group that is susceptible to nutritional problems, especially protein intake which tends to be less intake, so it affects the body mass index. Both of these problems directly or indirectly will also affect the quality of life of the elderly. This study aimed to determine the correlation between body mass index, protein intake and quality of life in the elderly.<br />Methods: In a cross-sectional design, a sample of 165 elderlies aged≥60 years were enrolled and randomized from three community health centers of Karanganyar Regency. The body mass index (BMI), height, weight, protein intake data were obtained through interviews using 24-hour recall form. The quality of life data was prepared through interviews using the WQOOL-BREF questionnaire.<br />Results: There was a significant correlation between protein intake and quality of life; however, there was no correlation between body mass index and the quality of life.<br />Conclusion: Protein intake was shown to have a significant relationship with quality of life in the elderly.
Body mass index,Protein intake,Quality of life,Elderly
https://ijns.sums.ac.ir/article_45831.html
https://ijns.sums.ac.ir/article_45831_9f530dc0b6e15350c59a8e48895558d8.pdf
Shiraz University of Medical Sciences
International Journal of Nutrition Sciences
2538-1873
2538-2829
4
4
2019
12
01
The Effect of Aqueous and Hydroalcoholic Extracts of the Mango Fruit on Development of Embryonic Tissues during Pregnancy
202
205
EN
Davood
Mehrabani
0000-0002-5738-1719
Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
mehrabad@sums.ac.ir
Sahar
Mehrvarz
00000000000000000000
Department of Biology, Jahrom Islamic Azad University, Jahrom, Iran
sa_mehrvarz@yahoo.com
Mina
Rabiee
0000-0002-7275-3365
Department of Genetics, Shahre-Kord Islamic Azad University, Shahre-Kord, Iran
mina.rabiee1368@gmail.com
10.30476/ijns.2019.83956.1040
Background: Mango fruit (Mangifera indica) is rich of phytoestrogens, polyphenols, calcium, iron and potassium which play an important role in bone and dental growth and development. The aim of this study was to determine the effect of M. indica on embryos in pregnant mice.<br /> Methods: In an experimental study, 24 pregnant mice were equally divided into 3 groups of those receiving aqueous extract of the mango fruit, its alcoholic extract and the control group receiving just distilled water. Animals were sacrificed at 19th day of pregnancy and embryos were removed and fixed in 10% formalin for histological studies.<br /> Results: No abnormality and teratogenic effects were noticed in bone, cartilage, liver, spleen, kidney, digestive tract and spinal cord tissues.<br /> Conclusion: Aqueous and hydroalcoholic extracts of the mango fruit (M. Indica) can be administered safely during pregnancy without any complications in body tissues an in bone and dental growth and<br /> development.
Mangifera indica,Fetus,Embryo,Teratogen
https://ijns.sums.ac.ir/article_45788.html
https://ijns.sums.ac.ir/article_45788_22a19301fd70a3e2de7a044f5eff2495.pdf