TY - JOUR ID - 45788 TI - The Effect of Aqueous and Hydroalcoholic Extracts of the Mango Fruit on Development of Embryonic Tissues during Pregnancy JO - International Journal of Nutrition Sciences JA - IJNS LA - en SN - 2538-1873 AU - Mehrabani, Davood AU - Mehrvarz, Sahar AU - Rabiee, Mina AD - Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AD - Department of Biology, Jahrom Islamic Azad University, Jahrom, Iran AD - Department of Genetics, Shahre-Kord Islamic Azad University, Shahre-Kord, Iran Y1 - 2019 PY - 2019 VL - 4 IS - 4 SP - 202 EP - 205 KW - Mangifera indica KW - Fetus KW - Embryo KW - Teratogen DO - 10.30476/ijns.2019.83956.1040 N2 - Background: Mango fruit (Mangifera indica) is rich of phytoestrogens, polyphenols, calcium, iron and potassium which play an important role in bone and dental growth and development. The aim of this study was to determine the effect of M. indica on embryos in pregnant mice. Methods: In an experimental study, 24 pregnant mice were equally divided into 3 groups of those receiving aqueous extract of the mango fruit, its alcoholic extract and the control group receiving just distilled water. Animals were sacrificed at 19th day of pregnancy and embryos were removed and fixed in 10% formalin for histological studies. Results: No abnormality and teratogenic effects were noticed in bone, cartilage, liver, spleen, kidney, digestive tract and spinal cord tissues. Conclusion: Aqueous and hydroalcoholic extracts of the mango fruit (M. Indica) can be administered safely during pregnancy without any complications in body tissues an in bone and dental growth and development. UR - https://ijns.sums.ac.ir/article_45788.html L1 - https://ijns.sums.ac.ir/article_45788_22a19301fd70a3e2de7a044f5eff2495.pdf ER -