@article { author = {Setavand, Zahra and Ekramzadeh, Maryam}, title = {Glycemic Control and Acne: A Review}, journal = {International Journal of Nutrition Sciences}, volume = {4}, number = {2}, pages = {59-64}, year = {2019}, publisher = {Shiraz University of Medical Sciences}, issn = {2538-1873}, eissn = {2538-2829}, doi = {10.30476/ijns.2019.81827.1016}, abstract = {Acne as a chronic inflammation involves pilosebaceous unit and is associated with hyperkeratosis and sebaceous hypersecretion. A high glycemic index (GI) and glycemic load (GL) diet may stimulate acne proliferative pathways affecting biochemical factors in acne. Although GI and GL have a prominent role in acne pathophysiology, few literatures assessed this association. This review was undertaken to summarize the published data regarding the effect of low glycemic load diet on acne lesions. A literature search was conducted in PubMed, Science direct, Google scholar up to January 2019. GI and GL are implicated in acne pathogenesis due to diet-induced hyperinsulinemia, stimulating a rise in IGF-1 concentrations and androgen hormones and as a result, amplifying acne-promoting pathways.}, keywords = {Acne,Acne Vulgaris,Glycemic index,Glycemic load,Insulin}, url = {https://ijns.sums.ac.ir/article_44934.html}, eprint = {https://ijns.sums.ac.ir/article_44934_6b9c0ddd80ad4a7765686e77ce2837f9.pdf} }