Document Type : Original Article
Authors
1
Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2
Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3
Comparative and Experimental Medicine Center, Shiraz University of Medical Sciences, Shiraz, Iran
4
Science and Research Branch, Islamic Azad University, Fars, Iran
5
Traditional Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
6
Shahre-Kord Branch, Islamic Azad University, Shahre-Kord, Iran
7
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
8
Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Background: Herbal medicine may have irreparable effects on fetal development. This study investigated the effect of Cariandrumsativum (coriander) aquous extract on mice fetal height and weight.
Methods:In an experimental study, 120 pregnant mice were divided into four equal groups. The control group was without any intervention. The experimental group received 3500, 5000 and 6500 mg/kg of aquous extract of coriander. The height and weight of the embryos were recorded in first, second and third week of pregnancy.
Results: The height and weight of embryos in experimental groups in first, second and third week was significantly lower than the control group.
Conclusion: Coriander (C. Sativum) aquous extract was shown to reduce the fetal height and weight in a dose-dependent manner. These findings can be added to the literature when coriander is going to be used during pregnancy.
Keywords
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