Intraoperative Magnesium Sulfate Infusion Enhances Neuroprotection and Muscle Relaxation during Brain Tumor Resection: A Case Report

Document Type : Case Report

Authors

1 Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

2 Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3 Department of Neurosurgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

Intraoperative neurophysiological monitoring (IONM) is a valuable technique used during brain tumor resections to assess and preserve neurological function. This case report investigates the impact of intraoperative magnesium sulfate infusion on neuroprotection and muscle relaxation in the context of IONM during brain tumor resection.
A 48-year-old male with altered awareness and occasional convulsive movements involving his right upper and lower limbs accompanied by progressive right-sided weakness and occasional sensory disturbances was diagnosed with a left temporal lobe tumor. He underwent craniotomy for tumor resection, with concurrent IONM and an intraoperative
magnesium sulfate infusion. The patient’s neurophysiological parameters, surgical outcomes, and postoperative recovery were analyzed, suggesting a potential synergistic effect between magnesium sulfate and IONM in optimizing patient outcomes.

Highlights

Mostafa Afsharianfar (Google Scholar)

Seyedeh Haniyeh Mortazavi (Google Scholar)

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