The Effect of Aquous Extract of Cariandrum Sativum on Fetal Weight and Height in Pregnant Mice

Document Type: Original Article

Authors

1 Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2 Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3 Comparative and Experimental Medicine Center, Shiraz University of Medical Sciences, Shiraz, Iran

4 Science and Research Branch, Islamic Azad University, Fars, Iran

5 Traditional Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

6 Shahre-Kord Branch, Islamic Azad University, Shahre-Kord, Iran

7 Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

8 Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

Background: Herbal medicine may have irreparable effects on fetal development. This study investigated the effect of Cariandrumsativum (coriander) aquous extract on mice fetal height and weight.
Methods:In an experimental study, 120 pregnant mice were divided into four equal groups. The control group was without any intervention. The experimental group received 3500, 5000 and 6500 mg/kg of aquous extract of coriander. The height and weight of the embryos were recorded in first, second and third week of pregnancy.
Results: The height and weight of embryos in experimental groups in first, second and third week was significantly lower than the control group. 
Conclusion: Coriander (C. Sativum) aquous extract was shown to reduce the fetal height and weight in a dose-dependent manner. These findings can be added to the literature when coriander is going to be used during pregnancy.

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