The Effects of Vitamin C in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review of Clinical Trials

Mosallanezhad, Zahra; Jalali, Mohammad; Eftekhari, Mohammad Hassan; Ahmadi, Afsane

doi:10.30476/ijns.2019.84611.1049

The Effects of Vitamin C in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review of Clinical Trials

Document Type : Review Article

Authors

Zahra Mosallanezhad ¹^{, 2}

Mohammad Jalali ¹^{, 2}

Mohammad Hassan Eftekhari ³

Afsane Ahmadi ⁴

¹ Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

² Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

³ Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

⁴ Research Center for Health Sciences, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran

10.30476/ijns.2019.84611.1049

Abstract

The present systematic review aimed to investigate the effects of vitamin C on the improvement of chronic obstructive pulmonary disease (COPD). Online databases (PubMed, Scopus, Embase, Cochrane Library and Web of Sciences) were systematically searched to find clinical trials evaluating the effects of vitamin C supplementation on COPD up to July 2019. After excluding irrelevant records, 3 studies were included. Two included studies demonstrated significant effect of vitamin C supplementation on
COPD improvement, but another study did not. In conclusion, vitamin C might have positive effects on COPD patients. But more future studies are needed to reach a definite conclusion.

Keywords

COPD

Vitamin C

Ascorbic acid