Association between Nutrition and Immune System: A Review

Document Type : Review Article


1 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

2 Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran

3 Department of Veterinary Medicine, Beyza Branch, Islamic Azad University, Beyza, Iran

4 Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran


Many human diseases are caused by infection with either viruses or bacteria. The proper functioning of the immune system is essential for the survival of any individual throughout life. The optimal immune response depends on an adequate nutrition and appropriate food pattern to prevent infection. For example, getting enough protein is important for optimal antibody production. Minerals and vitamins are forms of nutrients (called micronutrients) that have the appropriate capacity to support the immune system by providing preventive mediators of infectious diseases to reduce the rate of destruction of cells transported by free radicals or to help the better functioning of T-cells. Reduced intake of micronutrients such as vitamins A, E, C, D, B6, B9, and B12, as well as minerals such as zinc, magnesium, iron, selenium, and copper can decrease resistance to
infections. Therefore, it is necessary to design a review study that looks at the role of micronutrients in preventing infectious diseases.