The Correlation between Intake of Vitamin C and β-Carotene and Fasting Blood Sugar: A Cross-Sectional Analysis in Diabetic Patients of Fasa Cohort Study

Rajabi, Shirin; Rajabi, Farshad; Farhangdoost, Sarvenaz; Haghighat, Neda; Banihashemi, Seyed Hesamaddin

doi:10.30476/ijns.2023.99515.1247

The Correlation between Intake of Vitamin C and β-Carotene and Fasting Blood Sugar: A Cross-Sectional Analysis in Diabetic Patients of Fasa Cohort Study

Document Type : Original Article

Authors

Shirin Rajabi ¹

Farshad Rajabi ²

Sarvenaz Farhangdoost ²

Neda Haghighat ²

Seyed Hesamaddin Banihashemi ³

¹ Department of Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

² Laparoscopy Research Center, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran

³ Department of Surgery, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

10.30476/ijns.2023.99515.1247

Abstract

Background: Diet and nutrition are strongly implicated in the etiology of type 2 diabetes. This study has investigated whether low vitamin C and β-carotene intakes were associated with glycemic control in diabetic patients.
Methods: In a cross-sectional analysis of diabetic adult patients participating in Fasa Cohort Study, a 24-h dietary recall was used to assess intake of fruits, vegetables, vitamin C and β-carotene. The associations between vitamin C and β-carotene intakes and glycemic control were determined in 3 groups of normal glucose tolerance, pre-diabetes mellitus, and type 2 diabetes mellitus (T2DM) and the relationship between fasting blood glucose (FBS) and vitamin C and β-carotene intakes was
investigated.
Results: There were no differences between groups for intake of total vitamin C and β-carotene (p>0.05). An inverse relation was recognized between intake of total vitamin C and β-carotene and FBS (p<0.05).
Conclusion: A negative association was observed between FBS and intake of vitamin C and β-carotene; however more experimental studies are needed to establish whether increase in intake of vitamin C and β-carotene can improve FBS level and prevent T2DM.

Highlights

Shirin Rajabi (Google Scholar)

Neda Haghighat (Google Scholar)

Keywords

Vitamin C

β-carotene

Fasting blood glucose

Type 2 diabetes mellitus

Fasa Cohort Study