The Effect of Gastric Bypass and Sleeve Gastrectomy Surgery on the Level of Vitamin A, Iron, Copper, Ferritin, Hemoglobin, Vitamin D, Vitamin B12, Zinc and Cardiometabolic Factors in Patients with Morbid Obesity

Articles in Press

Document Type : Original Article

Authors

1 Laparoscopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2 Iranian Hospital Dubai, Iranian Red Crescent Society, Dubai, United Arab Emirates

3 Department of Nutrition, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran

10.30476/ijns.2025.104992.1386

Abstract

Background: Obesity is a significant global health issue and bariatric surgery has emerged as a critical intervention for sustainable weight loss and metabolic improvement in individuals with severe obesity. Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB) are the most commonly performed procedures, each with distinct mechanisms and outcomes. Comparative studies have highlighted varying outcomes between SG and RYGB, particularly in terms of weight loss, metabolic improvement, and postoperative complications. This study aimed to compare the baseline characteristics and subsequent outcomes of patients
undergoing SG and RYGB.
Methods: Weight loss, metabolic parameters, and several micronutrient levels including biochemical factors, lipid profile, vitamin A, Iron, copper, ferritin, hemoglobin, vitamin D, vitamin B12 and zinc over a 12-month follow-up period were compared in both groups.
Results: Both SG as well as RYGB led to substantial weight loss and improvement in lipid profile and glycemic control over 12 months. RYGB showed superior reductions in LDL cholesterol and total cholesterol compared to SG, indicating potential additional benefits of RYGB.
Conclusion: Both SG and RYGB were effective for weight loss and metabolic improvement, with RYGB showing superior long-term benefits in lipid profile management.

Highlights

Masoud Amini (Google Scholar)

Keywords

International Journal of Nutrition Sciences

Articles in Press, Accepted Manuscript
Available Online from 03 August 2025

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