The Effect of Purple Sweet Potato Jelly on Malondialdehyde and Fasting Blood Sugar in Experimental Type 2 Diabetic Rat Model

Document Type : Original Article


1 Graduate School of Nutrition Science, Sebelas Maret University, Surakarta, Indonesia

2 Anatomy Laboratory, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia


Background: Purple sweet potato jelly (Lpomea batatas L. Poir) 
can potentially be rich in anthocyanin and fiber with antioxidant and hypoglycemic properties that may be beneficial to T2DM sufferers. This study aimed to find out the influence of purple sweet potato jelly on MDA and FBS in experimental T2DM of rats. 
Methods: In an experimental research, 20 male Wistar rats were divided into four groups. Group 1 consisted of T2DM rats fed on standard diet (G1), while group 2, 3 and 4 were fed on standard diet of 7.47 g per 200 g 
of body weight containing 1.35 g (G2), 2.7 g (G3) and 5.4 g (G4) of purple sweet potato jelly, respectively. The MDA and FBS levels were checked at day 0 and 14. 
Results: After 14th day of intervention, the mean MDA level changed to 0.28±0.84 in G1, -4.08±0.54 in G2, -5.81±0.45 in G3 and -6.56±0.50 nmol/ml in G4, while the MDA level in G1 was significantly different from other groups (P=0.001). The Mean FBS level changed to 3.95±0.68 in G1, -114.06±3.11 in G2, -129.96±4.23 in G3 and -136.78±3.94 mg/dL in G4, whereas the FBS level of G1 was significantly different from other groups (P=0.001). 
Conclusion: Our findings revealed that purple sweet potato jelly when consumed for 14 days could significantly decrease MDA and FBS levels in type 2 diabetes mellitus rat model. Therefore, purple sweet potato can be introduced in literature an alternative herbal medicine in treatment of type 2 diabetes mellitus.