Document Type : Review Article
Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Anesthesia and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Nutrition Research Center, Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
Background: Argan oil is a natural vegetable oil recently received much attention because of ingredients such as tocopherols, particularly in its γ-isoform, polyphenols, and phytosterols which are rich sources of antioxidants with therapeutic eﬀects on cardiovascular diseases, diabetes, obesity, hypercholesterolemia, hypertension, hepatic disease, cancer, acne, sebum, and aging. One half tablespoon per day was shown to be eﬀective to prevent metabolic diseases.
Methods: The current systematic review and meta-analysis evaluated the eﬀect of argan oil on cardiovascular health. PubMed, Scopus, EMBASE, and Web of Science databases were searched from their beginning to August 2019. All clinical trials studied the eﬀect of argan oil on the systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), vitamin E, apolipoprotein A (Apo A) and apolipoprotein B (Apo B) levels for at least two weeks were included. Five studies underwent metaanalysis techniques using random-eﬀects models.
Results: Collective outcomes showed that argan oil increased the vitamin E level (SMD: 2.98, 95%CI: -0.51, 6.48, p =0.09) non-signifcantly compared with control group. Argan oil could signifcantly raise the Apo A level (SMD: 0.74, 95%CI: 0.39, 1.10, p <0.001), and decrease the Apo B level signifcantly (SMD: -0.58, 95%CI: -0.93, -0.23, p =0.001).
Conclusion: Our study showed that consumption of argan oil increased Apo-A and vitamin E levels, but further clinical studies on a larger number of patients are needed to explain and confrm the biological and clinical eﬀects of argan oil.