Evaluation of the Relationship between Insulin, Vitamin D Levels and Dietary Habits in Adults with Normal Weight and Obesity

Document Type : Original Article


Department of Nutrition and Dietetics, Faculty of Health Sciences, Baskent University, Ankara, Turkey


Background: Obesity and insulin resistance has been associated with vitamin D deficiency. Many studies have shown that vitamin D deficiency is associated with increased body weight, impaired glucose tolerance, insulin resistance, early onset of Type 2 diabetes mellitus (T2DM), coronary heart disease, mood disorders, and high blood pressure.
Methods: The study was carried out with a total of 170 subjects, including 121 females and 49 males, aged between 19-65. Individuals’characteristics, general dietary habits, anthropometric measurements, biochemical parameters, physical activity and mood status were evaluated
by the researcher.
Results: A total of 170 people with a mean age of 34.96±9.61 years participated in this study. Of the total participants, 121 were females. Individuals with a body mass index (BMI) of ≥25 had higher blood glucose (mg/dL), insulin (uU/mL), Homa-IR (mg/dL), and HbA1-C (%) levels and lower plasma vitamin D (ng/mL) level compared to those with a BMI of <25. It was shown that as the risk of eating disorders increased, insulin and Homa-IR values of the individuals increased too in direct
proportion and that Homa-IR values were higher in individuals with a higher risk of depression in direct proportion.
Conclusion: Regarding any body weight management, the people should be evaluated and followed up in terms of insulin and vitamin D levels, dietary habits and mood disorders.