The Role of Lithium Chloride in Nutrition and Stem Cell Growth Kinetics: A Review

Document Type: Review Article

Authors

1 Department of Molecular Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran

2 Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3 Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

4 Comparative and Experimental Medicine Center, Shiraz University of Medical Sciences, Shiraz, Iran

5 Li Ka Shing Center for Health Research and Innovation, University of Alberta, Edmonton, AB, Canada

6 Department of Biology, Kazeroon Branch, Islamic Azad University, Kazeroon, Iran

Abstract

Lithium chloride (LiCl) is an essential trace element and the smallest alkali metal with an atomic weight of 6.9 that is found in grains, vegetables and in supplemented drinking water sources that seems to have profound effects on human well-being, susceptibility to several diseases and stem cell growth kinetics. Much remains to be learned and understood about the implications of LiCl in nutrition and stem cell culture. This review is going to consider what is known about the nature
of this competition and the knowledge towards understanding of lithium biology and its application in medicine in osteomyopathology, immunity, neuroprotectionm, radio- and chemotherapy, cancer and proliferation of stem cells.

Keywords