Nutritional Status and Gastrointestinal Manifestations in Patients with Systemic Sclerosis in Ilam, Iran

Shafiei, Elham; Bazgir, Nasrin; Tahmasebi Ghorabi, Samaneh; Vahabzadeh, Davoud; Karimi Rouzbahani, Arian; Jamshidi, Reza; Bonyadi, Mahtab

doi:10.30476/ijns.2024.101752.1306

Nutritional Status and Gastrointestinal Manifestations in Patients with Systemic Sclerosis in Ilam, Iran

Document Type : Original Article

Authors

Elham Shafiei ¹

Nasrin Bazgir ²^{, 3}

Samaneh Tahmasebi Ghorabi ⁴

Davoud Vahabzadeh ²

Arian Karimi Rouzbahani ⁴^{, 5}

Reza Jamshidi ²

Mahtab Bonyadi ²

¹ Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran

² Non-Communicable Diseases Research Center, Ilam University of Medical sciences, Ilam, Iran

³ Department of Rheumatology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran

⁴ USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran

⁵ Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran

10.30476/ijns.2024.101752.1306

Abstract

Background: Systemic sclerosis is an incurable autoimmune fibrotic skin disease. Many factors were described as aetiology of SS, but the impact of nutritional factor is unknown. The aim of this study was to determine the nutritional status and gastrointestinal manifestations in patients with systemic sclerosis in Ilam, Iran.
Methods: In a case-control study, 47 people confirmed with systemic sclerosis disorders were enrolled as case group and 47 subjects as control group; while they were matched for age and BMI and compared statistically. Food frequency questionnaire (FFQ) and demographic
variables were collected for all participants.
Results: Meat and dairy consumption was higher among case group (Adjusted OR=5.1, p<0.01, CI=1.08-24.64; Adjusted OR=4.2, p<0.01,
CI=1.23-14.29, respectively); while there was a reduction for vegetables intake (Adjusted OR=0.09, p<0.05, CI=0.01-0.876).
Conclusion: An increase in meat and dairy consumption and reduction in intake of vegetables seems to be the causes for systemic sclerosis in patients in the area. Further evaluations in a large sample size with a longer follow-up duration are needed to verify these findings. The results can help health authorities when planning for patients with systemic sclerosis.

Highlights

Elham Shafiei (Google Scholar)

Nasrin Bazgir (Google Scholar)

Keywords

Systemic sclerosis

Nutritional status

Gastrointestinal manifestations