Vitamin D Deficiency and Hashimoto’s Thyroiditis in a Patient with Polycystic Ovary Syndrome and Ulcerative Colitis

Kumar, Jeevan; Kondaveeti, Devaki; Rayana, Supriya; Agamudi, Lavanya; Yedla, Hanuman Prasad

doi:10.30476/ijns.2025.104324.1354

Vitamin D Deficiency and Hashimoto’s Thyroiditis in a Patient with Polycystic Ovary Syndrome and Ulcerative Colitis

Document Type : Case Report

Authors

Jeevan Kumar ¹

Devaki Kondaveeti ¹

Supriya Rayana ¹

Lavanya Agamudi ²

Hanuman Prasad Yedla ³

¹ Department of Pharmacy Practice, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India

² Department of Pharmacy, Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh, India

³ Department of Gastroenterology, Hanuman’s Liver and Gastric Care, Guntur, Andhra Pradesh, India

10.30476/ijns.2025.104324.1354

Abstract

We present a 25-year-old woman with complaints of missing menstrual cycle for 3 months, and having a history of ulcerative colitis with no significant family history. The polycystic ovary syndrome (PCOS) was diagnosed by an ultra-sonogram of uterus. Lab investigation revealed the thyroid functional test, vitamin D, total RBC, hemoglobin, MCV, MCHC, total cholesterol, LDL cholesterol and non-HDL cholesterol of the patient to be in an abnormal range. The undertaken treatment included 75 mcg levothyroxine and supplements of vitamin D, methyl cobalamin, myoinositol, D-chiro-inositol and folic acid to provide a healthy menstrual cycle. We showed patient with ulcerative colitis can have risk of malnutrition and lead to vitamin D deficiency with a correlation with anti-TPO level; while treatment measures, diet modification and stress management technique improved the patient’s condition and menstrual cycle became normalized.

Highlights

Jeevan Kumar (Google Scholar)

Devaki Kondaveeti (Google Scholar)

Keywords

Vitamin D deficiency

Hashimoto thyroiditis

PCOS

Ulcerative colitis

Diet