Estimation of Calcium and Vitamin D Levels of Thalassemia Patients in Baghdad, Iraq

Articles in Press

Document Type : Original Article

Authors

1 College of Pharmacy, Al-Mustansiriyah University, Baghdad, Iraq

2 Basic Science Department, College of dentistry, Mustansiriyah University, Baghdad, Iraq

10.30476/ijns.2025.106136.1427

Abstract

Background: Beta thalassemia patients require lifelong blood transfusions that can lead to iron accumulation in tissues and a decreased vitamin D synthesis. This study determined vitamin D and calcium levels in thalassemia patients in Baghdad, Iraq.
Methods: In 2023, 100 adult patients of 15-25 years of both sexes who were regularly diagnosed with thalassemia in Center for Genetic Hematology at Ibn al-Baladi Hospital in Rusafa- Baghdad, Iraq were enrolled. Serum 25-OH-vitamin D and calcium were levels were assessed. Totally, 50 blood samples were collected from thalassemia patients together with 50 blood samples from healthy people as control for comparison.
Results: Vitamin D level was low in thalassemia patients. There was a significant difference in the decrease in vitamin D level between men and women (p=0.008). Females had a significantly higher calcium deficiency than males. The serum calcium level was low, and no significant difference was noticed between sexes (p=0.28). When comparing thalassemia rate, a significant difference was visible in vitamin D level (p=0.002). For calcium level, the difference between two groups was significant (p=0.01).
Conclusion: A significant difference was observed for vitamin D and calcium deficiency among thalassemia patients of both sexes when compared to healthy people.

Keywords

International Journal of Nutrition Sciences

Articles in Press, Accepted Manuscript
Available Online from 23 November 2025

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